Νίκησε το AIDS
Μεταμόσχευση μυελού «θεράπευσε πλήρως» ασθενή με HIV
Πηγή: news.in,gr
Ο αιματολόγος Τζέρο Χόιτερ ήταν επικεφαλής της ιατρικής ομάδας
Βερολίνο
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Ένας 42χρονος που ζούσε με τον ιό HIV και είχε εμφανίσει και λευχαιμία φαίνεται να απαλλάχθηκε οριστικά από τις δύο ασθένειες έπειτα από μεταμόσχευση μυελού των οστών με επιλεγμένο γενετικό προφίλ.
Οι Γερμανοί γιατροί του τονίζουν πάντως ότι πρόκειται για μεμονωμένη περίπτωση που πρέπει να μελετηθεί περαιτέρω, και όχι για ιατρική επανάσταση.
«Είναι μια ενδιαφέρουσα περίπτωση από ερευνητική άποψη» δήλωσε στο AFP o Ρόντολφ Τάουμπερ, καθηγητής στο πανεπιστημιακό Φιλανθρωπικό Νοσοκομείο του Βερολίνου, όπου νοσηλεύτηκε ο ασθενής. «Το να υποσχεθούμε όμως στα εκατομμύρια ανθρώπους που έχουν μολυνθεί από τον HIV ότι υπάρχει ελπίδα για θεραπεία, δεν θα ήταν αληθές» τόνισε.
Προστασία
Ο τυχερός 42xρονος θεραπεύτηκε επειδή το μόσχευμα κατά της λευχαιμίας έφερε ένα γονίδιο που ήταν γνωστό ότι προστατεύει από τον HIV. Zει σήμερα χωρίς φάρμακα για τον ιό και οι εξετάσεις στο αίμα, τον μυελό των οστών και διάφορα όργανά του παρέμεναν όλες καθαρές 20 μήνες μετά τη μεταμόσχευση. Ωστόσο κανείς δεν μπορεί να αποκλείσει το ενδεχόμενο ο ιός να κρύβεται ακόμα στον οργανισμό του και κάποια στιγμή να επανεμφανιστεί, διευκρινίζουν οι γιατροί.
Ο ασθενής, ένας Αμερικανός που ζει στη γερμανική πρωτεύουσα, ήταν θετικός στον HIV εδώ και μια δεκαετία. Κατέφυγε στο νοσοκομείο όταν εμφάνισε και λευχαιμία, η οποία αντιμετωπίστηκε αρχικά με χημειοθεραπεία.
Στη συνέχεια η ιατρική ομάδα προχώρησε σε μεταμόσχευση μυελού. Οι γιατροί φρόντισαν ώστε το μόσχευμα να είναι όχι μόνο συμβατό με το λήπτη, αλλά και να φέρει την προστατευτική ποικιλία Δέλτα 2 του γονιδίου CCR5.
Η ποικιλία αυτή μειώνει τον αριθμό των υποδοχέων CCΡ5 που χρησιμοποιεί ο HIV για να μολύνει τα T-κύτταρα του ανοσοποιητικού συστήματος. Οι γιατροί δεν ήταν εύκολο να βρουν δότη, δεδομένου ότι μόνο ένας στους 1.000 ανθρώπους ευρωπαϊκής καταγωγής φέρει σε δύο αντίγραφα τη Δέλτα 2.
Μετά τη μεταμόσχευση ο ασθενής σταμάτησε να παίρνει φάρμακα κατά του HIV, μια κίνηση που κανονικά θα οδηγούσε σε απότομη αύξηση των επιπέδων του ιού. Αυτό όμως δεν συνέβη.
Προηγούμενο
Το εντυπωσιακό φαινόμενο έχει εξάλλου παρατηρηθεί και στο παρελθόν, έστω και σε μεμονωμένα περιστατικά. Το 1999, δημοσίευση στην επιθεώρηση Medical Hypotheses επανεξέταζε τα αποτελέσματα από 32 προηγούμενες απόπειρες το διάστημα 1982-1996 και διαπίστωνε ότι ο ιός φαινόταν να είχε εκριζωθεί σε δύο περιπτώσεις.
«Το διάβασα συμπτωματικά το 1996. Το θυμήθηκα και σκέφτηκα ότι μπορεί να δούλευε» δήλωσε ο αιματολόγος Τζέρο Χόιτερ, επικεφαλής της γερμανικής ομάδας. Το πείραμα έφερε πράγματι εντυπωσιακά αποτελέσματα.
Το σίγουρο όμως είναι ότι η μεταμόσχευση μυελού δεν θα περάσει άμεσα στην κλινική πράξη για τη θεραπεία του AIDS . «Η διαδικασία αυτή δεν είναι προσαρμοσμένη για τη θεραπεία των ασθενών με HIV, ούτε τώρα ούτε στο κοντινό μέλλον» διευκρίνισε ο Χόιτερ.
Πριν από την επέμβαση, οι γιατροί χρησιμοποίησαν ισχυρά φάρμακα και ακτινοβολία για να καταστρέψουν το μολυσμένο μυελό του ασθενούς και να απενεργοποιήσουν το ανοσοποιητικό του σύστημα.
Η διαδικασία αυτή σκοτώνει το 20 με 30 τοις εκατό των υποψήφιων ληπτών μυελού.
Οι γιατροί προσανατολίζονται τώρα σε έρευνες για την εισαγωγή του Δελτα 2 στον οργανισμό των ασθενών με μεθόδους γονιδιακής θεραπείας, αντί με μεταμόσχευση.
Η περίπτωση του 42χρονου Αμερικανού δεν έχει ακόμα υποβληθεί σε επιστημονική επιθεώρηση για έλεγχο και δημοσίευση.
Newsroom ΔΟΛ, με πληροφορίες από Associated Press
Εμφάνιση αναρτήσεων με ετικέτα safety. Εμφάνιση όλων των αναρτήσεων
Εμφάνιση αναρτήσεων με ετικέτα safety. Εμφάνιση όλων των αναρτήσεων
20 Αυγ 2007
Recognizing and Avoiding Spyware
Cyber Security Tip ST04-016
Recognizing and Avoiding Spyware
Because of its popularity, the internet has become an ideal target for
advertising. As a result, spyware, or adware, has become increasingly
prevalent. When troubleshooting problems with your computer, you may
discover that the source of the problem is spyware software that has
been installed on your machine without your knowledge.
What is spyware?
Despite its name, the term "spyware" doesn't refer to something used
by undercover operatives, but rather by the advertising industry. In
fact, spyware is also known as "adware." It refers to a category of
software that, when installed on your computer, may send you pop-up
ads, redirect your browser to certain web sites, or monitor the web
sites that you visit. Some extreme, invasive versions of spyware may
track exactly what keys you type. Attackers may also use spyware for
malicious purposes.
Because of the extra processing, spyware may cause your computer to
become slow or sluggish. There are also privacy implications:
* What information is being gathered?
* Who is receiving it?
* How is it being used?
How do you know if there is spyware on your computer?
The following symptoms may indicate that spyware is installed on your
computer:
* you are subjected to endless pop-up windows
* you are redirected to web sites other than the one you typed into
your browser
* new, unexpected toolbars appear in your web browser
* new, unexpected icons appear in the task tray at the bottom of
your screen
* your browser's home page suddenly changed
* the search engine your browser opens when you click "search" has
been changed
* certain keys fail to work in your browser (e.g., the tab key
doesn't work when you are moving to the next field within a form)
* random Windows error messages begin to appear
* your computer suddenly seems very slow when opening programs or
processing tasks (saving files, etc.)
How can you prevent spyware from installing on your computer?
To avoid unintentionally installing it yourself, follow these good
security practices:
* Don't click on links within pop-up windows - Because pop-up
windows are often a product of spyware, clicking on the window may
install spyware software on your computer. To close the pop-up
window, click on the "X" icon in the titlebar instead of a "close"
link within the window.
* Choose "no" when asked unexpected questions - Be wary of
unexpected dialog boxes asking whether you want to run a
particular program or perform another type of task. Always select
"no" or "cancel," or close the dialog box by clicking the "X" icon
in the titlebar.
* Be wary of free downloadable software - There are many sites that
offer customized toolbars or other features that appeal to users.
Don't download programs from sites you don't trust, and realize
that you may be exposing your computer to spyware by downloading
some of these programs.
* Don't follow email links claiming to offer anti-spyware software -
Like email viruses, the links may serve the opposite purpose and
actually install the spyware it claims to be eliminating.
As an additional good security practice, especially if you are
concerned that you might have spyware on your machine and want to
minimize the impact, consider taking the following action:
* Adjust your browser preferences to limit pop-up windows and
cookies - Pop-up windows are often generated by some kind of
scripting or active content. Adjusting the settings within your
browser to reduce or prevent scripting or active content may
reduce the number of pop-up windows that appear. Some browsers
offer a specific option to block or limit pop-up windows. Certain
types of cookies are sometimes considered spyware because they
reveal what web pages you have visited. You can adjust your
privacy settings to only allow cookies for the web site you are
visiting (see Browsing Safely: Understanding Active Content and
Cookies and Evaluating Your Web Browser's Security Settings for
more information).
How do you remove spyware?
* Run a full scan on your computer with your anti-virus software -
Some anti-virus software will find and remove spyware, but it may
not find the spyware when it is monitoring your computer in real
time. Set your anti-virus software to prompt you to run a full
scan periodically (see Understanding Anti-Virus Software for more
information).
* Run a legitimate product specifically designed to remove spyware -
Many vendors offer products that will scan your computer for
spyware and remove any spyware software. Popular products include
Lavasoft's Ad-Aware, Webroot's SpySweeper, PestPatrol, and Spybot
Search and Destroy.
* Make sure that your anti-virus and anti-spyware software are
compatible - Take a phased approach to installing the software to
ensure that you don't unintentionally introduce problems (see
Coordinating Virus and Spyware Defense for more information).
_________________________________________________________________
Authors: Mindi McDowell, Matt Lytle
_________________________________________________________________
Produced 2007 by US-CERT, a government organization.
Note: This tip was previously published and is being re-distributed
to increase awareness.
Terms of use
http://www.us-cert.gov/legal.html
This document can also be found at
http://www.us-cert.gov/cas/tips/ST04-016.html
Recognizing and Avoiding Spyware
Because of its popularity, the internet has become an ideal target for
advertising. As a result, spyware, or adware, has become increasingly
prevalent. When troubleshooting problems with your computer, you may
discover that the source of the problem is spyware software that has
been installed on your machine without your knowledge.
What is spyware?
Despite its name, the term "spyware" doesn't refer to something used
by undercover operatives, but rather by the advertising industry. In
fact, spyware is also known as "adware." It refers to a category of
software that, when installed on your computer, may send you pop-up
ads, redirect your browser to certain web sites, or monitor the web
sites that you visit. Some extreme, invasive versions of spyware may
track exactly what keys you type. Attackers may also use spyware for
malicious purposes.
Because of the extra processing, spyware may cause your computer to
become slow or sluggish. There are also privacy implications:
* What information is being gathered?
* Who is receiving it?
* How is it being used?
How do you know if there is spyware on your computer?
The following symptoms may indicate that spyware is installed on your
computer:
* you are subjected to endless pop-up windows
* you are redirected to web sites other than the one you typed into
your browser
* new, unexpected toolbars appear in your web browser
* new, unexpected icons appear in the task tray at the bottom of
your screen
* your browser's home page suddenly changed
* the search engine your browser opens when you click "search" has
been changed
* certain keys fail to work in your browser (e.g., the tab key
doesn't work when you are moving to the next field within a form)
* random Windows error messages begin to appear
* your computer suddenly seems very slow when opening programs or
processing tasks (saving files, etc.)
How can you prevent spyware from installing on your computer?
To avoid unintentionally installing it yourself, follow these good
security practices:
* Don't click on links within pop-up windows - Because pop-up
windows are often a product of spyware, clicking on the window may
install spyware software on your computer. To close the pop-up
window, click on the "X" icon in the titlebar instead of a "close"
link within the window.
* Choose "no" when asked unexpected questions - Be wary of
unexpected dialog boxes asking whether you want to run a
particular program or perform another type of task. Always select
"no" or "cancel," or close the dialog box by clicking the "X" icon
in the titlebar.
* Be wary of free downloadable software - There are many sites that
offer customized toolbars or other features that appeal to users.
Don't download programs from sites you don't trust, and realize
that you may be exposing your computer to spyware by downloading
some of these programs.
* Don't follow email links claiming to offer anti-spyware software -
Like email viruses, the links may serve the opposite purpose and
actually install the spyware it claims to be eliminating.
As an additional good security practice, especially if you are
concerned that you might have spyware on your machine and want to
minimize the impact, consider taking the following action:
* Adjust your browser preferences to limit pop-up windows and
cookies - Pop-up windows are often generated by some kind of
scripting or active content. Adjusting the settings within your
browser to reduce or prevent scripting or active content may
reduce the number of pop-up windows that appear. Some browsers
offer a specific option to block or limit pop-up windows. Certain
types of cookies are sometimes considered spyware because they
reveal what web pages you have visited. You can adjust your
privacy settings to only allow cookies for the web site you are
visiting (see Browsing Safely: Understanding Active Content and
Cookies and Evaluating Your Web Browser's Security Settings for
more information).
How do you remove spyware?
* Run a full scan on your computer with your anti-virus software -
Some anti-virus software will find and remove spyware, but it may
not find the spyware when it is monitoring your computer in real
time. Set your anti-virus software to prompt you to run a full
scan periodically (see Understanding Anti-Virus Software for more
information).
* Run a legitimate product specifically designed to remove spyware -
Many vendors offer products that will scan your computer for
spyware and remove any spyware software. Popular products include
Lavasoft's Ad-Aware, Webroot's SpySweeper, PestPatrol, and Spybot
Search and Destroy.
* Make sure that your anti-virus and anti-spyware software are
compatible - Take a phased approach to installing the software to
ensure that you don't unintentionally introduce problems (see
Coordinating Virus and Spyware Defense for more information).
_________________________________________________________________
Authors: Mindi McDowell, Matt Lytle
_________________________________________________________________
Produced 2007 by US-CERT, a government organization.
Note: This tip was previously published and is being re-distributed
to increase awareness.
Terms of use
http://www.us-cert.gov/legal.html
This document can also be found at
http://www.us-cert.gov/cas/tips/ST04-016.html
8 Ιουν 2007
21 Μαρ 2007
16 Μαρ 2007
How to Remove Spyware From Your PC
και κάτι χρήσιμο, από το περιοδικό PC World
* Visit the Spyware & Security Info Center for the latest in the fight
against spyware and spam:
http://www.pcworld.com/tc/spyware/?tk=nl_spxctr
Almost everyone needs to deal with spyware at one point or another.
This week we present PC World security expert Andrew Brandt's detailed
advice on how to recognize and remove spyware from your computer, plus
a review of the latest ZoneAlarm antivirus and antispyware security
suite. We've also got free software downloads that will protect you
from these nasties.
Top Story
"How to Remove Spyware From Your PC":
http://www.pcworld.com/article/id,129094/article.html?tk=nl_spxhow
Security Product Reviews
"ZoneAlarm Internet Security Suite 7.0":
This suite performs well and is easy to use, but it lacks a targeted
antiphishing component.
http://www.pcworld.com/article/id,129514/article.html?tk=nl_spxrvw
Free Security Software
AVG Anti-Virus:
Free program protects against viruses and hackers.
http://www.pcworld.com/downloads/file/fid,15202/description.html?tk=nl_spxdwn
Ad-Aware SE Personal:
This free antispyware program with a solid scanning engine lacks
real-time protection.
http://www.pcworld.com/downloads/file/fid,7423/description.html?tk=nl_spxdwn
Spybot Search & Destroy:
Perennial favorite antispyware tool has lots of settings.
http://www.pcworld.com/downloads/file/fid,22262/description.html?tk=nl_spxdwn
* Visit the Spyware & Security Info Center for the latest in the fight
against spyware and spam:
http://www.pcworld.com/tc/spyware/?tk=nl_spxctr
Almost everyone needs to deal with spyware at one point or another.
This week we present PC World security expert Andrew Brandt's detailed
advice on how to recognize and remove spyware from your computer, plus
a review of the latest ZoneAlarm antivirus and antispyware security
suite. We've also got free software downloads that will protect you
from these nasties.
Top Story
"How to Remove Spyware From Your PC":
http://www.pcworld.com/article/id,129094/article.html?tk=nl_spxhow
Security Product Reviews
"ZoneAlarm Internet Security Suite 7.0":
This suite performs well and is easy to use, but it lacks a targeted
antiphishing component.
http://www.pcworld.com/article/id,129514/article.html?tk=nl_spxrvw
Free Security Software
AVG Anti-Virus:
Free program protects against viruses and hackers.
http://www.pcworld.com/downloads/file/fid,15202/description.html?tk=nl_spxdwn
Ad-Aware SE Personal:
This free antispyware program with a solid scanning engine lacks
real-time protection.
http://www.pcworld.com/downloads/file/fid,7423/description.html?tk=nl_spxdwn
Spybot Search & Destroy:
Perennial favorite antispyware tool has lots of settings.
http://www.pcworld.com/downloads/file/fid,22262/description.html?tk=nl_spxdwn
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